Methods and devices for controlling a motion position of a multi-leaf collimator are provided. An example device includes a control system and two trolleys connected with the control system. The multi-leaf collimator includes two rows of leaves arranged in opposite sides, and each of the trolleys carries one row of the leaves. Each trolley is movably connected with a first screw rod and driven by a first motor connected with the first screw rod. A first encoder is arranged on the first motor and operable to feed back first position information of the trolley to the control system. A displacement sensor is arranged on the first screw rod and operable to feed back second position information of the trolley to the control system. The control system is operable to control the motion position of the trolley based on the first position information and the second position information.