BELL, ROBERT J.A.,COSTELLO, JOSEPH F.,LIM, DANIEL,MANCINI, ANDREW
申请号:
CA3061905
公开号:
CA3061905A1
申请日:
2018.05.24
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention provides methods for cancers associated with a TERTpromoter mutation in a subject. In someembodiments, the methods comprise administering to the subject atherapeutically effective amount of an agent that specifically reducesor inhibits GA binding protein transcription factor beta subunit 1 longisoform (GABPBIL) expression or function.