GENOMIC ENGINEERING OF PLURIPOTENT CELLS

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专利权人:

Fate Therapeutics; Inc.

发明人:

Bahram Valamehr,Ramzey Abujarour,Tom Tong Lee,Weijie Lan,Raedun Clarke,Ryan Bjordahl

申请号：

US16379668

公开号：

US20190271005A1

申请日:

2019.04.09

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/