The Board of Trustees of the University of Illinois
发明人:
Michael F. INSANA,Minwoo KIM
申请号：
US16442729
公开号：
US20190380684A1
申请日:
2019.06.17
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Described herein are methods and apparatus for increasing sensitivity of ultrasound imaging of fluid flow in an object of interest. Ultrasound imaging of blood perfusion can be performed without contrast enhancement. Embodiments include transforming a spatiotemporal echo data array into a three-dimensional perfusion data array having a spatial dimension, a slow-time dimension, and a frame-time dimension, and filtering the perfusion data array with an eigen passband clutter filter. The clutter filter can increase sensitivity and utility of ultrasound imaging of fluid flow. In some aspects, the method can yield blood flow signal power and perfusion values well separated from tissue clutter. In an example, enhancements to ischemic tissue perfusion maps in a murine model are shown.
