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Middel for behandling av betennelsestarmsykdom
专利权人:
TLA Targeted Immunotherapies AB
发明人:
Winqvist, Ole,Thörn, Magnus
申请号:
NO20081539
公开号:
NO341189B1
申请日:
2008.03.28
申请国别(地区):
NO
年份:
2017
代理人:
摘要:
A method of treating inflammatory bowel disease (IBD) comprises collecting regulatory T cells in an activated or non-activated state from a patient's sentinel lymph nodes draining bowel segments with or without IBD, optionally activating the cells by contacting them with a cytokine and an antigen extract obtained from an inflamed bowel segment, expanding the T cells in vitro, and re-infusing the expanded T cell to the patient. Also disclosed are methods for obtaining sentinel nodes, for expanding T cells, for re-establishing the TH1/TH2 balance in the patient suffering from Crohn's disease, and corresponding uses of the expanded T cells, the cytokine and of antigen extract, as well as of correspondingly activated and expanded T cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
thörn, magnus
winqvist, ole
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