The Board of Trustees of the Leland Stanford Junior University
发明人:
Bryan R. Smith,Eliver Ghosn
申请号：
US16353743
公开号：
US20190275175A1
申请日:
2019.03.14
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention provides compositions and methods for visualizing particular tissues and delivering one or more therapeutics to that tissue using single-walled carbon nanotubes (SWNTs), which are taken up and delivered to target tissues by specific monocytes in the body. The delivery of SWNT to target tissues allows the visualization of the affected tissue for diagnostics and therapy in diseases where the specific monocyte is implicated in the disease pathogenesis. These nanotubes can be conjugated to a peptide, such as RGD, which helps direct the SWNT-containing monocytes to the vascular endothelium.
