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Material and preparation of biocompatible hemostatic water soluble chitosan
专利权人:
发明人:
Muhammad Yar,Lubna Shahzadi
申请号:
US15587064
公开号:
US10059809B2
申请日:
2017.05.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A water soluble biocompatible hydrogel having an amino sugar linked to a hydrophilic polymer is disclosed. Linkage of the amino sugar and hydrophilic polymer may be provided by an imine-amine bond between an amine of the amino sugar and a primary amine of the hydrophilic polymer. The linkage between the amino sugar and the hydrophilic polymer may be provided by reacting an amine of the amino sugar and a primary amine of the hydrophilic polymer with a formate ester in an acidic solution. Water soluble biocompatible polymer having an amino sugar linked to a hydrophilic polymer may be cast into films, dried into gauze and/or combined with salt solutions to provide injectable gels.
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