Franciscus Petrus Thomas Baaijens;Martijn Antonius Johannes Cox;Mirjam Petronella Rubbens
发明人:
Franciscus Petrus Thomas Baaijens,Mirjam Petronella Rubbens,Martijn Antonius Johannes Cox
申请号:
US13122387
公开号:
US09109310B2
申请日:
2009.10.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates a multilayer preform obtained by electro-spinning, which preform is suitable as a scaffold for a prosthesis, which preform comprises at least one layer of microfibers and at least one layer of nanofibers, wherein the pore size of the at least one layer of microfibers is in the range of 1-300 micrometer and in that the pore size of the at least one layer of nanofibers is in the range of 1-300 micrometer. The present invention also relates to a method of producing said preform. The present invention also relates to the use of the present preform as a substrate for growing human or animal tissue thereon. The present invention furthermore relates to a method for growing human or animal tissue on a substrate, wherein the present preform is used as the substrate.