The United States of America, as represented by the Secretary, Department of Health and Human Services;The Regents of the University of Cali; as represented by the Secretary;Eastern Virginia Medical School;The United States of America; Department of Health and Human Services;Thomas Jefferson University
发明人:
Maloney, David J.,Holman, Theodore,Jadhav, Ajit,Simeonov, Anton,Bantukallu, Ganesha Rai,Nadler, Jerry L.,Holinstat, Michael
申请号：
AU2011255627
公开号：
AU2011255627A1
申请日:
2011.05.18
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Disclosed are inhibitors of human 12-lipoxygenase of Formula (I) or (II), wherein R, R, R, and R are as defined herein, that are useful in treating or preventing a 12-lipoxygenase mediated disease or disorder, e.g., diabetes. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal.
