[Problem to be solved] To provide a drug delivery system capable of delivering a drug into a cell expressing a VEGF receptor. [Solution] Provided is a VEGF-binding peptide-drug complex in which a drug is bound to a C-terminal amino acid /or an N-terminal amino acid of a VEGF-binding peptide and is incorporated into a VEGF receptor-expressing cell by endocytosis of a VEGF receptor, the VEGF-binding peptide having a helix-loop-helix structure including an A block that includes a peptide forming an ±-helix structure and is positioned on an N-terminal side, a C block that includes a peptide forming an ±-helix structure and is positioned on a C-terminal side, and a B block that includes a peptide linking the A block and the C block by a covalent bond.
