OTSUKA PHARMACEUTICAL CO., LTD.;OSAKA UNIVERSITY;INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC.
发明人:
KUBO, Hiroshi,SOGO, Shinji,SUGIYAMA, Haruo
申请号:
PH12015501361
公开号:
PH12015501361B1
申请日:
2015.06.16
申请国别(地区):
PH
年份:
2015
代理人:
摘要:
The present invention relates to a method for activating helper T cells, which includes the step of activating helper T cells by adding a WT1 peptide to antigen presenting cells, wherein the WT1 peptide has the ability to bind to an MHC class II molecule selected from HLA-DRB1*08:02 molecule, an HLA-DRB1*13:02 molecule, an HLA-DRB1*14:03 molecule, an HLA-DRB1*14:05 molecule, an HLA-DQB1*03:02 molecule and an HLA-DQB1*04:01 molecule.