Disclosed are systems and methods for enabling the acquisition of physiological parameters of a mammal or other specimen using thermo-mechanical responses (e.g., temperature, pressure and alternatively acceleration, pulse, position). In accordance with one example embodiment, a monitoring device for wired and/or wireless sensors is used to acquire a series of sensor signals that are attached to achieve the physiological measurements of a mammal vital signs is provided. The device includes a Temperature-Pressure (T-P) sensor configured to attach to respiration, vascular pressure and audio points of the mammal in a manner suitable for obtaining the acquired individual sensor electrical signal. The sensor system is configured to attach to alternative locations of the specimen in a manner suitable for obtaining electrical signals in communication with a signal receiver and transmitter. Physiological parameters, such as those associated with vital signs (temperature, pulse, respiration, etc.), can be obtained using the monitoring device and associated sensors.
