Dental cleaning device that comprises: - a frame (11) comprising an outer portion (12) apt to be gripped by a user and an internal portion (13), fixable to the outer portion (12) and shaped so as to be inserted into a user's oral cavity and superimpose on a dental arch; - a cleaning body (14) extending along a curvilinear trajectory (A) showing the trajectory of development of a dental arch; the cleaning body (14) is supported by the internal portion (13), has at least a brush element (15) movable with respect to the inner portion (13) and is configured in such a way that, in use, interferes with a plurality of teeth of at least a dental arch of the user; - actuating means (16), fixed to the outer portion (12) and mechanically connected to the at least a brush element (15) to operate it.