Monika ERMANN,Guenther LAMETSCHWANDTNER,Patricia Leonie AMOUZEGH,Russell Stuart CRAFT,Thomas HANKE,Timothy Robin JAMES,Severine Danielle JONES,Hans LOIBNER,Pui Leng LOKE,Ina STERNBERGER,Anton STUETZ,R
申请号：
US15554354
公开号：
US20180170888A1
申请日:
2016.02.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to bicyclic tetrahydrothiazepine of formula (I), wherein R1 to R3, X1, X2 and R18 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising such compounds as well as their use as medicaments, especially in methods for the treatment or prevention of a neoplastic and/or infectious disease and in vitro methods.
