PROBLEM TO BE SOLVED: To provide a Helicobacter pylori proliferation inhibitor which contains simply and massively produced compound and specifically inhibits proliferation of the Helicobacter pylori, safe and not producing a resistant bacteria.SOLUTION: The Helicobacter pylori inhibitor comprises N-acetylglucosamine and either of an N-acetylglucosamine &alpha-linked monosaccharide derivative represented by formula (1) or an N-acetylglucosamine &alpha-linked oligosaccharide derivative represented by formula (2). Formula (1) GlcNAc1-&alpha-O-Y. (Y is a (substituted) aromatic ring-containing group, an acyl group in the formula). Formula (2) GlcNAc1-&alpha-Gal-Z. (Z is a terminal hydrogen atom, a 1-8C alkoxyl group, a sugar chain, a peptide or a lipid, in the formula.).COPYRIGHT: (C)2007,JPO&INPIT【課題】簡便にかつ大量に製造でき、特異的にピロリ菌増殖を抑制する化合物を含み、安全で、耐性菌を生じさせないピロリ菌増殖抑制剤の提供。【解決手段】ピロリ菌増殖抑制剤は、GlcNAcと、式(1)で表されるN-アセチルグルコサミンα結合単糖誘導体、又は式(2)で表されるN-アセチルグルコサミンα結合オリゴ糖誘導体の少なくとも何れかを含有する。 GlcNAc1-α-O-Y ・・・(1)(式(1)中、Yは、置換基を有していてもよい芳香環含有基;アシル基を示す) GlcNAc1-α-Gal-Z ・・・(2)(式(2)中、Zは、末端水素基、炭素数1~8のアルコキシ基、糖鎖、ペプチドまたは脂質を示す)【選択図】なし
