Joanna Kubler-Kielb,Evguenii Vinogradov,Rachel Schneerson,Haijing Hu,Stephen H. Leppla,John B. Robbins
申请号:
US14563920
公开号:
US20150093412A1
申请日:
2014.12.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided are immunogenic compositions and methods for eliciting an immune response against B. anthracis and other bacteria that contain 3-methyl-3-hydroxybutyrate- or 3-hydroxybutyrate-substituted saccharides. Conjugates of 3-methyl-3-hydroxybutyrate- or 3-hydroxybutyrate-substituted saccharides elicit an effective immune response against B. anthracis spores in mammalian hosts to which the conjugates are administered.