PROBLEM TO BE SOLVED: To provide a new medicinal composition for angiogenic therapy.SOLUTION: The present invention discloses the medicinal composition for the angiogenic therapy containing, as effective components, at least one kind selected from the group comprising substances having a vasodilation effect and/or a platelet aggregation restraining effect, and substances generating the substances, and a gene encoding an angiogenesis factor. an enhancement agent for an angiogenic effect by a gene of encoding the angiogenesis factor, containing, as the effective components, at least one kind selected from the group comprising the substances having the vasodilation effect and/or the platelet aggregation restraining effect, and the substances generating the substances, an angiogenic medicine containing a prostacyclin synthetase gene as an active component, the medicinal composition for the angiogenic therapy containing an ets-1 gene and other gene encoding the angiogenesis factor as effective components, an enhancement agent for the angiogenic effect by the other gene encoding the angiogenesis factor, containing the ets-1 gene as the effective component, and an angiogenic medicine containing the ets-1 gene as an effective component.
