The present invention relates to a tilapia cultivable in complete seawater and a breeding method thereof, and more particularly, to a method for breeding tilapia cultivated in complete seawater, comprising: (1) preparing tilapia (Oreochromis mossambicus) (2) performing a seawater adaptation experiment on the tilapia prepared in the step (1) (3) producing a first hybrid by crossing the female and the female of the tilapia surviving in the step (2) (4) repeating the seawater adaptation test on the first hybrid produced in step (3) (5) producing a second hybrid by mutating the cancer and the number of the first hybrid in survival in the seawater adaptation experiment of step (4) And (6) repeating the step of adapting the seawater adaptation to the hybrids in the same manner as in the above steps (4) to (5), and crossing the hybrids surviving in the seawater adaptation experiment to produce new hybrids again .The tilapia cultivable in the seawater according to the present invention and the breeding method thereof have the following effects.First, it has been recognized that freshwater fish species are inadequate in terms of frequency due to the concern of infection with Ganoderma lucidum. By breeding tilapia in complete seawater, it is possible to eliminate the concern about infection with ganoderma lucidum against tilapia, It can be cultivated in the sea, and it is possible to ingest tilapia harmless to the human body without abuse of antibiotics.Second, in the case of tilapia, there was a problem of negative recognition of tilapia of consumers due to the fact that the conventional light salt property was exploited and mixed with seaweed fishes, but it was possible to breed in perfect sea water, It can be used, and it will be able to escape the negative perception such as cheating with sea fish.Third, when it is possible to breed in complete seawater, it can be cultivated in a larger quantity than existing land raising facilities through cage culture, etc., and it is p