FIELD: chemistry.SUBSTANCE: invention relates to a novel compound of formula (II), which has the properties of a cell proliferation inhibitor. Fabric or organ fibrosis is renal interstitial fibrosis, glomerulosclerosis, hepatic fibrosis, pneumosclerosis, IPF, peritoneal fibrosis, myocardial fibrosis, dermatofibrosis, skeletal muscle fibrosis, pancreatic fibrosis, hepatic cirrhosis, myosarcoma, neurofibroma, pulmonary interstitial fibrosis, or vascular fibrosis. In formula (II),where each of Q1 and Q2 independently represents N or CH； J is -O- or -(CH2)m-； Y is -O-, -(CH2)m-O-, -N(R6) - or -(CH2)m-； where each is (CH2)m-O- and -(CH2)m- independently and optionally substituted with one or more substitutes independently selected from C1-4 alkyl, each R5 independently represents,where each E1, E2 and E3 independently represents N or CR7； each T and T1 independently represents -NR8-, -O-, -S- or -CR7R7a-； each R7 and R7a independently represents H； where each R5 independently and additionally substituted with one or more substituents independently selected from H, F, Cl, Br, I, C1-4 alkyl, C2-4 alkenyl, C1-4 alkoxy, C1-4 haloalkyl, cyano, amino, C1-4 alkylamino, phenyl, and C1-4 haloalkoxy； each R6 independently represents H or C1-4 alkyl； each R8 independently represents H； each R1a is independently H, F, Cl, Br, or I； R3 is methyl, ethyl, propyl, butyl, or tert-butyl； and each R4 is independently H, F, Cl, Br, or I； each m is independently 1 or 2； and each n or p is independently 0, 1, 2, 3 or 4.EFFECT: compound can be used in preparing a medicinal agent for preventing, controlling, treating or relieving the severity of tissue or organ fibrosis.11 cl, 1 tbl, 69 exИзобретение относится к новому соединению формулы (II), которое обладает свойствами ингибитора клеточной пролиферации. Соединение может найти применение в производстве лекарственного препарата для профилактики, регулирования, лечения или облегчения тяжести фиброза ткани или органа. Фиброз ткани или органа пр
