PROBLEM TO BE SOLVED: To provide a gemcitabine composition which can stably store gemcitabine as an aqueous solution for a long time without other special additive agents, and to provide a medicine package which consists of a fundamental unit container and an auxiliary unit container which contain prescribed quantities of the gemcitabine composition, respectively.SOLUTION: A gemcitabine composition contains an aqueous gemcitabine solution that gemcitabine or a pharmaceutically acceptable salt thereof dissolves in an aqueous solvent. The aqueous gemcitabine solution is adjusted in a pH in a range of 8.0 or more and less than 9.0, and the aqueous gemcitabine solution does not contain an organic solvent. A medicine package is a package for one-time administration of gemcitabine which consists of a fundamental unit container and an auxiliary unit container which contain prescribed quantities of the gemcitabine composition, respectively.COPYRIGHT: (C)2016,JPO&INPIT【課題】ゲムシタビンを、他の特別な添加剤なしに、水溶液で長時間安定して保管できるゲムシタビン組成物、前記組成物を基本単位容器および補助単位容器に分量して含む医薬パッケージを提供すること。【解決手段】ゲムシタビン組成物は、ゲムシタビンまたはその薬学的に許容可能な塩が水性溶媒に溶解したゲムシタビン水溶液を含み、前記ゲムシタビン水溶液は、pHが8.0以上9.0未満に調整され、前記ゲムシタビン水溶液は、有機溶媒を含まないことを特徴とする。医薬パッケージは、前記組成物を基本単位容器および補助単位容器に分量して含むゲムシタビンの1回投与用パッケージである。【選択図】図1
