Substituted cyclic acetic acid derivatives for the treatment of metabolic disorders农业专利-农业学术服务平台

专利权人:: TAKEDA PHARMACEUTICAL COMPANY LIMITED;SCOHIA PHARMA, INC.;思可海雅药品株式会社;武田药品工业株式会社;武田藥品工業株式會社;思可海雅藥品株式會社

发明人:: 见渡诚司,見渡誠司,宫本泰史,宮本泰史,渡部浩史,中山弥生,中山彌生,人见优子,人見優子,会田淳平,會田淳平,高仓信幸,高倉信幸,古川英纪,古川英紀,野口直义,野口直義,平田泰啓,河西静夫,河西靜夫,小林俊威,前川毅志,其他发明人请求不公开姓名,其他發明人請求不公開姓名

摘要：: The present application provides novel aromatic ring compounds with GPR40 agonist activity and GLP ￣ 1 secretory promoting effect. The application relates to a compound or a salt thereof represented by formula (I), wherein each symbol is described in the specification, which has GPR40 agonist activity and GLP ￣ 1 secretory promoting effect, which can be used to prevent or treat cancer, obesity, diabetes, hypertension, hyperlipidemia, heart failure, diabetic complications, metabolic syndrome, myopenia, etc., and can provide excellent curative effect.本申請提供了可具有GPR40激動劑活性和GLP‑1促分泌作用的新型芳族環化合物。本申請涉及由式(I)表示的化合物或其鹽，其中每個符號如說明書中所述，其具有GPR40激動劑活性和GLP‑1促分泌作用，其可用於預防或治療癌症、肥胖、糖尿病、高血壓、高脂血症、心力衰竭、糖尿病並發症、代謝綜合徵、肌少症等，並可提供優異的療效。