LIAU, Brian B.,PATEL, Anoop P.,SIEVERS, Cem,BERNSTEIN, Bradley E.
申请号：
EP16873494
公开号：
EP3386594A4
申请日:
2016.03.24
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present invention provides compositions and methods for the treatment of drug-tolerant glioblastoma, and in particular glioblastoma stem cells. Specifically, the methods comprise contacting a glioblastoma stem cell with a platelet-derived growth factor receptor alpha inhibitor and one or more of a histone lysine demethylase inhibitor and a Notch inhibitor.
