A four-wheeled rescue litter (FWRL) comprised of an elongated upper rail that is vertically spaced from an elongated lower rail by a plurality of vertical posts. Attached to the elongated lower rail is a litter base that can be permanently attached or removably attached which allows the litter base to be removed for maintenance, or to replace a damaged litter base. Near the front end of the elongated lower rail is attached a pair of swivel wheels that allow the FWRL to be easily steered, and near the rear end of the elongated lower rail is a pair of fixed wheels that stabilize the FWRL when been moved. Near the front end of the elongated upper rail is located a yoke having an attached handle that is used to pull or push the FWRL. When the handle is not in use, it can be rotated and placed against the upper rail. Extending from the front of the FWRL is a vehicle interface attachment structure that facilitates the attachment of the FWRL to a vehicle by use of a ball hitch.