Inc.;Brigham and Womens Hospital;Brigham and Women's Hospital
发明人:
Thon, Jonathan N.
申请号：
AU2016321116
公开号：
AU2016321116A1
申请日:
2016.01.19
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
A system and method for generating biological products. In some aspects, the system includes a first substrate having formed therein a plurality of inlet channel extending substantially along a longitudinal direction, and a second substrate having formed therein a plurality of outlet channel corresponding to the plurality of inlet channel and extending substantially along the longitudinal direction, the second substrate configured to releasably engage the first substrate. The system also includes a permeable membrane, arranged between the substrates, forming microfluidic pathways between respective inlet and outlet channels and configured to selectively capture biological source material capable of generating biological products, wherein at least one channel is tapered transversally to control a pressure differential profile regulating perfusion through the permeable membrane.
