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COMPOSITION FOR TREATMENT OF BRAIN CANCER AND METHOD OF MANUFACTURING EXTRACT FROM CEDRELA SINENSIS JUSS
专利权人:
LTD.;황성연;JEONG, KYUNG CHAE;정경채;KOREA BIO MEDICAL SCIENCE INSTITUTE CO.;주식회사한국전통의학연구소;HWANG, SUNG YEOUN;KOREA BIO MEDICAL SCIENCE INSTITUTE CO., LTD.
发明人:
HWANG, SUNG YEOUN,황성연,JEONG, KYUNG CHAE,정경채
申请号:
KR1020110005485
公开号:
KR1020120084135A
申请日:
2011.01.19
申请国别(地区):
KR
年份:
2012
代理人:
摘要:
PURPOSE: A composition containing Ailanthus altissima peel extract and pharmacologically acceptable carriers is provided to induce brain cancer cell apoptosis and to be applied to various pharmaceutical formulations. CONSTITUTION: A composition for treating brain cancer contains Ailanthus altissima peel extract which is prepared by dipping pulverized Ailanthus altissima peel in an aliphatic polar solvent as an active ingredient. The survival rate of U-87 MG cell line after treating 8.0 x10^3 of U-87 MG cell line in 100 ug/ml of an extract solution for 48 hours is 30% or less. The aliphatic polar solvent is alcohol of 1-5 carbon atoms.본 발명은 건조된 저근백피(樗根白皮, CEDRELA SINENSIS JUSS) 분쇄물로부터 지방족 극성 용매를 이용하여 추출되고 유효성분인 저근백피 추출물 및 약리학적으로 허용 가능한 담체들을 포함하는 뇌암 치료용 조성물을 제공한다. 상기 저근백피 추출물은 미량만으로도 뇌암 관련 세포의 사멸 및 증식 억제를 유도할 수 있어 다양한 약학적 제형에 폭 넓게 적용될 수 있다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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