Daniel Garrido,J. Bruce German,Carlito B. Lebrilla,David A. Mills
申请号:
US15079949
公开号:
US20160287680A1
申请日:
2016.03.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.