anthracycline-derived conjugate (pnu), drug-protein binding (bpdc) conjugate, method for producing a drug-protein binding (bpdc) conjugate, use of a protein-binding protein (bpdc) conjugate and pharmaceutical composition

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专利权人:

NBE THERAPEUTICS AG

发明人:

ROGER RENZO BEERLI,ULF GRAWUNDER

申请号：

BR112017013661

公开号：

BR112017013661A2

申请日:

2015.12.23

申请国别(地区):

BR

年份:

2018

代理人:

摘要：

The present invention relates to an anthracycline (pnu) derivative conjugate comprising an anthracycline derivative pnu-159682 having formula (i) or formula (ii) which additionally comprises an x? l1? 12? 13? y (figure 3a).a presente invenção refere-se a um conjugado derivado de antraciclina (pnu) que compreende um derivado da antraciclina pnu-159682 tendo a fórmula (i) ou fórmula (ii) que adicionalmente compreende uma estrutura de ligação x ? l1 ? l2 ? l3 ? y (figura 3a).

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/