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MICROWAVE ENABLED PORTABLE, LABEL-FREE, HIGH-THROUGHPUT DETECTION AND CONTENT SENSING SYSTEM FOR LAB ON A CHIP PLATFORMS
专利权人:
REN, CAROLYN LIQING;YESILOZ, GURKAN
发明人:
REN, CAROLYN LIQING,YESILOZ, GURKAN,BOYBAY, MUHAMMED SAID
申请号:
CA20172963807
公开号:
CA2963807(A1)
申请日:
2017.04.11
申请国别(地区):
加拿大
年份:
2018
代理人:
摘要:
This study reports a microwave-microfluidics integrated approach capable of performing droplet detection at high-throughput as well as content sensing of individual droplets without chemical or physical intrusion. The sensing system consists of a custom microwave circuitry and a spiral-shaped microwave resonator that is integrated with microfluidic chips where droplets are generated. The microwave circuitry is very cost effective by using off-the-shelf components only. It eliminates the need for bulky benchtop equipment, and provides a compact, rapid and sensitive tool compatible for Lab-on-a-Chip (LOC) platforms. To evaluate the resonator's sensing capability, it was first applied to differentiate between single-phase fluids which are aqueous solutions with different concentrations of glucose and potassium chloride respectively by measuring its reflection coefficient as a function of frequency. The minimum concentration assessed was 0.001 g ml-1 for potassium chloride and 0.01 g ml-1 for glucose. In the drop
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