TRUSSARDI RENÉ,GALLEY GUIDO,NORCROSS ROGER,PFLIEGER PHILIPPE
申请号:
NZ61682012
公开号:
NZ616820A
申请日:
2012.06.06
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed herein are compounds of formula (I) wherein the substituents are as defined herein or to a pharmaceutically suitable acid addition salt thereof. Examples being (S)-6-ethoxy-N-(2-fluoro-4-(morpholin-2-yl)phenyl)nicotinamide and 1-(3-cyano-benzyl)-3-((S)-2-fluoro-4-morpholin-2-yl-phenyl)-urea. These compounds are suitable for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson&rsquos disease, neurodegenerative disorders, Alzheimer&rsquos disease, epilepsy, migraine, hypertension, substance abuse, metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.