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5-aminocyclylmethyl-oxazolidin-2-one derivatives
专利权人:
ACTELION PHARMACEUTICALS LTD.
发明人:
HUBSCHWERLEN, CHRISTIAN,RUEEDI, GEORG,SURIVET, JEAN-PHILIPPE,ZUMBRUNN ACKLIN, CORNELIA
申请号:
TW97149419
公开号:
TWI441636B
申请日:
2008.12.18
申请国别(地区):
TW
年份:
2014
代理人:
摘要:
The invention relates to antibacterial compounds of formula I wherein one or two of U, V, W, and X represent N, the rest represent CH or, in the case of X, may also represent CRa wherein Ra is fluorine R1 represents alkoxy, halogen or cyano R2 represents H, CH2OH, CH2N3, CH2NH2, alkylcarbonylaminomethyl or triazol-1-ylmethyl R3 represents H, or, when n is 1, R3 may also represent OH, NH2, NHCOR6 or triazol-l-yl A represents CR4 K represents O, NH, OCH2, NHCO, NHCH2, CH2NH, CH2CH2, CH=CH, CHOHCHOH or CHR5 R4 represents H or together with R5 forms a bond, or also R4 can represent OH when K is not O, NH, OCH2 or NHCO R5 represents OH or together with R4 forms a bond R6 represents alkyl m is 0 or 1 and n is 0 or 1 and G is as defined in the description and to salts of such compounds.
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