IM, HO TAEKKR,임호택,KWON, TAEK KWANKR,권택관,YOUN, SEUNG BINKR,윤승빈,KIM, YONG ILKR,김용일,PARK, JAE HYUNKR,박재현,WOO, JONG SOOKR,우종수
申请号:
KR1020150133358
公开号:
KR1020170034707A
申请日:
2015.09.21
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
The present invention is to provide an oral solid formulation comprising roflumilast or a pharmaceutically allowable salt thereof as an active ingredient, polyvinyl alcohol as a bonding agent, and a pharmaceutically allowable additive, and a preparation method thereof. According to the present invention, the oral solid formulation comprising roflumilast uses polyvinyl alcohol as a bonding agent so solubility of roflumilast is increased, and an elution rate and bioavailability are increased.COPYRIGHT KIPO 2017본 발명은 활성성분으로서 로플루밀라스트 또는 약제학적으로 허용 가능한 그의 염, 결합제로서 폴리비닐알콜, 및 약제학적으로 허용 가능한 첨가제를 포함하는 경구용 고형제제 및 그 제조방법을 제공한다.