WHITFILL, TRAVIS MICHAEL,DENG, MING-DE,DODDS, DAVID RICHARD
申请号：
CA3088851
公开号：
CA3088851A1
申请日:
2019.01.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure provides recombinant Staphylococcus bacterium (e.g. S.epidermidis) that are dependent on D-alanine for growth. In one aspect, the disclosure features a recombinant Staphylococcus bacterium comprising two inactivated alanine racemase genes (?alr1?alr2)； and an inactivated D-alanine aminotransferase (dat) gene. In another aspect, the disclosure features a method of making the recombinant Staphylococcus bacterium.
