Continuous administration of l-dopa, dopa decarboxylase inhibitors, catechol-o-methyl transferase inhibitors and compositions for same

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专利权人:

NEURODERM LTD

发明人:

YACOBY-ZEEVI ORON,NEMAS MARA

申请号：

NZ61091111

公开号：

NZ610911A

申请日:

2011.11.15

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Disclosed is a pharmaceutically acceptable composition comprising: (i) 2.5% to 30% by weight levodopa carbidopa and 9% to 30% by weight arginine, wherein the composition has a pH of 8 to 10 at 25°C or (ii) 2% to 20% by weight levodopa 1% to 6% by weight carbidopa and arginine, meglumine, or both arginine and meglumine, wherein the composition has a pH of 9.1 to 9.8 at 25°C. Also disclosed is the use of the composition in treatment of a neurological or movement disorder.

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