Dispiropyrrolidine derivatives

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专利权人:

Daiichi Sankyo Company Limited

发明人:

Wakabayashi Takanori,Yoshida Keisuke,Setoguchi Masaki,Taniguchi Toru,Uoto Kouichi,Yamaguchi Akitake,Miyazaki Masaki,Sugimoto Yuuichi,Yoshida Shoko

申请号：

NZ71058512

公开号：

NZ710585A

申请日:

2012.03.09

申请国别(地区):

NZ

年份:

2017

代理人:

摘要：

The disclosure relates to (2S,5R)-5-({ [(3’R,4’S,5’R)-6’’-chloro-4’-(2-chloro-3- fluoropyridin-4-yl)-4,4-dimethyl-2’’-oxo-1’’,2’’-dihydrodispiro[cyclohexane-1,2’-pyrrolidine-3’,3’’-indole]-5’-yl]carbonyl} amino)tetrahydro-2H-pyran-2-carboxylic acid. It also relates to compositions and anticancer agents comprising this compound and their use in treating lung cancer, breast cancer, prostate cancer, colon cancer, acute myeloid leukemia, malignant lymphoma, malignant melanoma, retinoblastoma, neuroblastoma, or sarcoma.

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