Thomas Dull;Deborah A. Farson;Luigi Naldini;Rochelle Witt
发明人:
Luigi Naldini,Thomas Dull,Deborah A. Farson,Rochelle Witt
申请号:
US11460136
公开号:
US08846385B2
申请日:
2006.07.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.