A measuring device for the non-invasive measurement of physiological parameters is suited to detect and localize by way of self diagnosis diseases such as, for example, inflammations, tumors or arteriosclerosis. The measuring device includes at least one optical measuring unit, an evaluation unit processing the measuring signals, and a unit for the acquisition of local tissue parameters such as fat content, water content and/or blood perfusion. The evaluation unit is designed such that at least one local metabolic parameter is determined, in particular the local oxygen consumption, from the signals furnished by the optical measuring unit and obtained from tissue parameters. Moreover, the measuring device enables the non-invasive determination of the glucose concentration.
