The present invention proposes a device (100) for regulating cuff pressure in endotracheal tubes, comprising a barrel (10) for guiding a plunger (20), the plunger (20) being adapted to travel along a main longitudinal axis (A) of said barrel, thereby defining a cavity (C) with variable volume within the barrel, the device (100) further comprises a passage (11) adapted to allow fluid transfer communication to and from the cavity (C), and one or more biasing member (30) adapted to bias the plunger (20) towards said passage (11).