Alan Hunter,Xiangyang Wang,Timothy Pabst,Michaela Wendeler,Jihong Wang,Kendall Carey,Robert Strouse,Johnson Varghese
申请号：
US14342017
公开号：
US09598687B2
申请日:
2012.08.31
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present application relates to methods for purifying recombinant coagulation factor proteins, including for example, prothrombin (Factor II). In embodiments, the methods provide purified prothrombin that exhibit increased bioactivity and reduced levels of thrombin, thereby increasing the safety of the prothrombin. Also provided are purified recombinant coagulation factor proteins.
