Vinayak G. Gore;Hemant M. Mande;Sandeep G. Mekde;Rahul A. Bhalerao;Madhukar S. Patil
发明人:
Vinayak G. Gore,Madhukar S. Patil,Rahul A. Bhalerao,Hemant M. Mande,Sandeep G. Mekde
申请号:
US13124337
公开号:
US08883851B2
申请日:
2009.10.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.