COMPOSITIONS TARGETING PKC-THETA AND USES AND METHODS OF TREATING PKC-THETA PATHOLOGIES, ADVERSE IMMUNE RESPONSES AND DISEASES

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专利权人:

发明人:

申请号：

EP12800478.5

公开号：

EP2720705A2

申请日:

2012.06.15

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The invention relates to compositions, methods and uses of inhibitors of binding between PKC&thetas and CD28, and modulating an undesirable or aberrant immune response, disorder or disease, an inflammatory response, disorder or disease, inflammation or an autoimmune response, disorder or disease. Compositions include inhibitors of binding between PKC&thetas and CD28, which include, among others, PKC&thetas, CD28 and Lck sequences, subsequences, variants and modified forms, and polymorphisms.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/