Michael Sierks,Shanta Boddapati,Srinath Kasturirangan
申请号:
US13395011
公开号:
US08617549B2
申请日:
2010.09.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides for the treatment of Alzheimers disease. More specifically, a recombinant bispecific antibody fragment that simultaneously blocks beta-secretase activity while also promoting alpha-secretase activity, comprising a first portion and a second portion, wherein the first portion blocks beta secretase activity and the second portion promotes alpha-secretase activity.