The present invention concerns the cosmetic use, by topical administration, of an extract of Tapirira guianensis, for stimulating the expression of perlecan and/or dystroglycan and/or VE-cadherin and/or claudin-5, in particular in the extracellular matrix and/or in the epithelial basement membrane, in particular the dermoepidermal junction. It also concerns a method of cosmetic treatment comprising the application onto at least one area in question of healthy skin and/or healthy mucosa and/or healthy scalp of an extract of Tapirira guianensis or of a cosmetic composition comprising such an extract for stimulating the expression of perlecan and dystroglycan and/or VE-cadherin and/or claudin-5, in particular in the extracellular matrix and/or in the epithelial basement membrane, in particular the dermoepidermal junction. It also concerns a cosmetic composition comprising an extract of Tapiriraguianensis and a topically acceptable cosmetic carrier. It finally concerns an extract of Tapirira guianensis or a dermatological composition containing an extract of Tapirira guianensis and a dermatologically acceptable carrier for use, by topical administration, in the treatment and/or prevention of rosacea, des telangiectasias, and/or pathologies of the oral and/or ocular mucosa.La présente invention concerne l'utilisation cosmétique par voie topique d'un extrait de Tapirira guyanensis, pour stimuler l'expression du perlécane et/ou du dystroglycane et/ou de la VE-cadhérine et/ou de la claudine-5, en particulier dans la matrice extracellulaire et/ou dans la membrane basale épithéliale, notamment la jonction dermo-épidermique. Elle concerne également un procédé de soin cosmétique comprenant l'application sur au moins une zone concernée de la peau saine et/ou muqueuse saine et/ou du cuir chevelu sain d'un extrait de Tapirira guyanensis ou d'une composition cosmétique comprenant un tel extrait pour stimuler l'expression du perlécane et du dystroglycane et/ou de la VE-cadhérine et/
