A system adapted to assisting patients manage asthma includes a wearable sensor for detection of asthma symptoms and inhaler use, having a microphone capable of generating an electrical signal indicative of asthma symptoms or inhaler use； a processor with firmware adapted to process the electrical signal to determine potential asthma symptoms and inhaler use； and store the electrical signal in the memory when the electrical signal potentially corresponds asthma symptoms or inhaler use. In particular embodiments, the system includes an electronic asthma diary including detected asthma symptoms and detected inhaler usage, both with timestamps, and a prescribed treatment protocol. Protocol firmware processes detected asthma symptoms an inhaler usage recorded in the asthma diary to determine if asthma is controlled, and if asthma is not determined controlled determines if a treatment change is authorized； if treatment change is authorized the treatment change is displayed in human-readable form.
