PURIFICATION DE CONJUGUÉS A L'AIDE D'HYDROXYAPATITE

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专利权人:

NOVARTIS AG

发明人:

申请号：

EP08826340.5

公开号：

EP2180901B1

申请日:

2008.07.17

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

This application relates to methods for the purification of saccharide antigen-carrier protein conjugates. In particular, the invention provides a method for purifying saccharide antigen-carrier protein conjugates from free carrier protein, such as CRM197, using hydroxyapatite. The invention further relates to methods of preparing vaccines, using this method.

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中国工程科技知识中心

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