5,6-DIHYDRO -11 H-INDOLO[2,3-B]QUINOLIN-11-ONES EN TANT QU'INHIBITEURS D'ALK

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专利权人:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人:

CHEN, JIANYONG,LIU, LIU,DONG, XUYUAN,YANG, CHAO-YIE,MCEACHERN, DONNA,WANG, SHAOMENG

申请号：

CA3044384

公开号：

CA3044384A1

申请日:

2017.11.17

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present disclosure provides compounds represented by Formula( I), and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7, E and (B) are as defined as set forth in the specification. The present disclosure also provides compounds of Formula ( I) for use to treat a condition or disorder responsive to inhibition of ALK such as cancer.

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