DERIVES DE N-(PHENYL SUBSTITUE)-SULFONAMIDE EN TANT QU'INHIBITEURS DE KINASE

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专利权人:

NERVIANO MEDICAL SCIENCES S.R.L.

发明人:

BINDI, SIMONA,CARENZI, DAVIDE,MOTTO, ILARIA,PULICI, MAURIZIO

申请号：

CA3029097

公开号：

CA3029097A1

申请日:

2017.06.19

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The invention relates to N-(substituted-phenyl)-sulfonamide compounds, which are extremely useful as inhibitors of protein kinases (e.g. PERK kinase) and accordingly can be used for the treatment of cell proliferative disorders, such as cancer, or diseases associated with activated unfolded protein response pathways, such as Alzheimer's disease. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.

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