Disclosed are oral care compositions and the use of such oral care compositions for inhibiting co-aggregation of oral bacteria and inhibiting bacterial growth. Also disclosed are methods for inhibiting co-aggregation of oral bacteria and inhibiting bacterial growth. The oral care composition includes cranberry extract non-dialyzable material, in which the cranberry extract non-dialyzable material is present in an amount effective to inhibit co-aggregation of oral bacteria and/or inhibit bacterial growth.本發明揭示口腔保健組成物及此等口腔保健組成物於抑制口腔細菌共聚集及抑制細菌生長上之用途。亦揭示用於抑制口腔細菌共聚集及抑制細菌生長的方法。該口腔保健組成物包含蔓越莓萃出物非透析性物質,其中蔓越莓萃出物非透析性物質係以有效抑制口腔細菌共聚集及/或抑制細菌生長之量存在。