Dipeptoid prodrugs and the use thereof

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专利权人:

Alexandros Vakalopoulos;Peter Nell;Katja Zimmermann;Barbara Albrecht-Küpper;Ursula Krenz;Hans-Georg Lerchen;Joerg Keldenich;Daniel Meibom

发明人:

Hans-Georg Lerchen,Daniel Meibom,Alexandros Vakalopoulos,Barbara Albrecht-Küpper,Joerg Keldenich,Katja Zimmermann,Peter Nell,Ursula Krenz

申请号：

US13132991

公开号：

US08741834B2

申请日:

2009.12.03

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present application relates to dipeptide-like prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methyl}sulfanyl)-4-(4-{[2,3-dihydroxypropyl]oxy}phenyl)pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.

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