BOWMAN, LYLE, M.,CHANDRASEKARAN, S., KUMAR,ARCHIBALD, ROY, DUANE,PHAM, STEPHEN,MUFSON, DAVID
申请号:
EP08796298
公开号:
EP2211617A4
申请日:
2008.07.18
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to formulations of concentrated azalide antibiotics and methods for making and using them. Specifically, the invention relates to a method of treating an infection comprising administering to a patient in need thereof, an effective amount of a concentrated aqueous azalide antibiotic formulation made according to the method comprising dissolving an azalide antibiotic in an aqueous solution comprising a strong acid. The invention also relates to methods for making concentrated aqueous azalide antibiotic formulations for use in pulmonary infection, a nasopharyngeal infection, an otic infection, an ocular infection, a dermal or a vaginal infection. The invention also relates to concentrated aqueous azalide antibiotic formulations made by dissolving an azalide antibiotic in an aqueous solution comprising a strong acid.