The invention relates to a joint prosthesis with a shaft made of a titanium alloy. According to the invention, at least the shaft (10) is precision cast and has a centered cubical crystalline structure. A titanium allow with this crystalline structure (so-called ß-titanium alloy) has an advantageously low modulus of elasticity, which is well-adapted to the physiological requirements. In addition, the embodiment as a finished casting enables a complex shaping. Especially effective is an embodiment as a femoral prosthesis (1) for an artificial hip joint, which has a longitudinally extended shaft (10) with grooves (14) and sawtooth-like projections (15) for bone anchoring.